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EPX anticorps (CF®594)

Cet anticorps anti-EPX est un anticorps Souris Monoclonal détectant EPX dans FACS et IF. Adapté pour Humain.
N° du produit ABIN6173714

Aperçu rapide pour EPX anticorps (CF®594) (ABIN6173714)

Antigène

Voir toutes EPX Anticorps
EPX (Eosinophil Peroxidase (EPX))

Reactivité

  • 40
  • 6
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 28
  • 15
Souris

Clonalité

  • 27
  • 16
Monoclonal

Conjugué

  • 22
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp EPX est conjugé à/à la CF®594

Application

  • 16
  • 16
  • 12
  • 11
  • 7
  • 7
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

Clone

AHE-1
  • Fonction

    Mouse Monoclonal anti-Eosinophil Peroxidase (AHE-1), CF594 Conjugate

    Attributs du produit

    Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogène

    Human eosinophils from a patient with hypereosinophilic syndrome

    Isotype

    IgG1 kappa
  • Indications d'application

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    Commentaires

    MCF-7 cells. Tonsil

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    100 μg/mL

    Buffer

    PBS/0.1 % BSA/0.05 % azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Protect from light
  • Antigène

    EPX (Eosinophil Peroxidase (EPX))

    Autre désignation

    Eosinophil Peroxidase

    Sujet

    Eosinophil peroxidase heavy chain, EPER, EPO, EPP, EPX, EPX PEN, PERE

    Poids moléculaire

    70 kDa (55 kDa-Heavy Chain, 15 kDa-Light Chain)

    ID gène

    8288, 279259

    UniProt

    P11678
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