FSHR anticorps (CF®405S)
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- Antigène Voir toutes FSHR Anticorps
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FSHR est conjugé à/à la CF®405S
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Fonction
- Mouse Monoclonal anti-FSH Receptor (FSHR/1400), CF405S Conjugate
- Attributs du produit
- Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its ? and ? subunits. While the ? subunit of FSH is involved in the binding of FSH to the receptor, the ? subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant human full-length FSHR protein
- Clone
- FSHR-1400
- Isotype
- IgG1
- Top Product
- Discover our top product FSHR Anticorps primaire
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- Indications d'application
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA
- pH 9.0
- or 10 mM citrate buffer
- pH 6.0
- for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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Uterine Carcinoma
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- Autre désignation
- FSH Receptor (FSHR Produits)
- Synonymes
- anticorps FSHRO, anticorps LGR1, anticorps ODG1, anticorps FSH-R, anticorps eFSHR, anticorps FSHRE, anticorps fshr, anticorps FSHR, anticorps fshr-A, anticorps GTHR-I, anticorps zfGTHR-I, anticorps LOC100304505, anticorps follicle stimulating hormone receptor, anticorps follicle stimulating hormone receptor L homeolog, anticorps follicle-stimulating hormone receptor, anticorps FSHR, anticorps fshr, anticorps Fshr, anticorps fshr.L, anticorps Bm1_17785, anticorps LOC100304505
- Sujet
- Follicle-stimulating hormone receptor, Follitropin receptor, FSH receptor, FSH-R, FSHRO, LGR1, ODG1, ovarian dysgenesis 1
- Poids moléculaire
- 75 kDa
- ID gène
- 2492, 1428
- UniProt
- P23945
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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