HIV-1 p24 anticorps (CF®594)

N° du produit ABIN6186520

L’anticorps Souris Monoclonal anti-HIV-1 p24 a été validé pour ELISA, IF, ICC et Coat. Il convient pour détecter HIV-1 p24 dans des échantillons de Human Immunodeficiency Virus (HIV).

Aperçu rapide pour HIV-1 p24 anticorps (CF®594) (ABIN6186520)

Antigène: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Reactivité: Human Immunodeficiency Virus (HIV)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HIV-1 p24 est conjugé à/à la CF®594

Application: ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Coating (Coat)

Clone: P24-661

Détail du produit anti-HIV-1 p24 anticorps (CF®594)

Fonction: Mouse Monoclonal anti-HIV p24 (p24/661), CF594 Conjugate

Attributs du produit: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4 T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant HIV-1 Gag p24 protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Immunocytochemistry Acetone or paraformaldehyde fixed 0.5-1 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Commentaires:

HIV-1 infected cells or tissues.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur HIV-1 p24

Antigène: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Autre désignation: HIV p24

Classe de substances: Viral Protein

Sujet: Capsid protein p24, Human immunodeficiency virus type 1 p24, HIV1gp1, HIV-1 Gag p24

Poids moléculaire: 24 kDa (mature), 55 kDa & 41 kDa (precursors)

ID gène: 155348