CD81 anticorps (CF®640R)
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- Antigène Voir toutes CD81 Anticorps
- CD81
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Reactivité
- Humain, Souris, Rat
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD81 est conjugé à/à la CF®640R
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Application
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Functional Studies (Func)
- Fonction
- Mouse Monoclonal anti-CD81 / TAPA-1 (1.3.3.22), CF640R Conjugate
- Attributs du produit
- This antibody This antibody recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- B-Cell line derived from a Burkitt lymphoma
- Clone
- 1-3-3-22
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD81 Anticorps primaire
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- Indications d'application
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For functional studies, order Ab without azide
- Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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Ramos, Daudi, Raji, U266, HUT-78, HUT-102, Jurkat, HL-60, KG1a, A293, A431, MG63, and human lymphocytes. Tonsil or Liver.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- CD81
- Autre désignation
- CD81 / TAPA-1 (CD81 Produits)
- Synonymes
- anticorps Tapa-1, anticorps Tapa1, anticorps Tspan28, anticorps CVID6, anticorps S5.7, anticorps TAPA1, anticorps TSPAN28, anticorps CD81 molecule, anticorps CD81 molecule b, anticorps CD81 antigen, anticorps Cd81 molecule, anticorps CD81, anticorps cd81b, anticorps Cd81
- Sujet
- CD81, Target of the antiproliferative antibody 1 (TAPA-1), Tetraspanin-28, Tspan-28
- Poids moléculaire
- 26 kDa
- ID gène
- 975, 54457
- UniProt
- P60033
- Pathways
- Inositol Metabolic Process, Hepatitis C
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