ETS1 anticorps (AA 137-230)

N° du produit ABIN6187635

Cet anticorps Souris Monoclonal détecte spécifiquement ETS1 dans WB, IHC, IF et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ETS1 anticorps (AA 137-230) (ABIN6187635)

Antigène: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ETS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: ETS1-1282

Détail du produit anti-ETS1 anticorps

Épitope: AA 137-230

Fonction: Mouse Monoclonal anti-ETS1-/ (ETS1/1282), Purified, BSA-free

Attributs du produit: ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Purification: Purified

Immunogène: Recombinant human ETS1 fragment (aa137-230) (exact sequence is proprietary)

Isotype: IgG

Information d'application

Indications d'application: Flow cytometry 0.5-1 μg/million cells in 0.1 mL

• Immunohistology (formalin) 1-2 μg/mL
• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
• Western blotting 1-2 μg/mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

HepG2 and HeLa cells. Tonsil, Skin, Pancreas, Kidney and Lymphoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS (no BSA, no azide)

Agent conservateur: Azide free

Détails sur ETS1

Antigène: ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))

Autre désignation: ETS1-

Sujet: Avian erythroblastosis virus E26 (v ets) oncogene homolog 1, ETS1, EWSR2, p54, v-ets erythroblastosis virus E26 oncogene homolog 1

Poids moléculaire: 54 kDa

ID gène: 2113, 369438

UniProt: P14921