TIMP3 anticorps (AA 175-211) (CF®405S)

N° du produit ABIN6188510

Cet anticorps anti-TIMP3 est un anticorps Lapin Polyclonal détectant TIMP3 dans FACS, IF et IHC (f). Adapté pour Humain, Souris, Rat, Boeuf (Vache), Chien et Cheval.

Aperçu rapide pour TIMP3 anticorps (AA 175-211) (CF®405S) (ABIN6188510)

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMP3 est conjugé à/à la CF®405S

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: PAb

Détail du produit anti-TIMP3 anticorps (CF®405S)

Épitope: AA 175-211

Fonction: Rabbit Polyclonal anti-TIMP3 CF405S Conjugate

Attributs du produit: TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: The amino acid sequence (aa175-211), used as the immunogen for TIMP3 Ab, is 100% homologous in human, cow, dog and horse, and 94% homologous in mouse and rat.

Isotype: IgG

Information d'application

Indications d'application: Immunohistology formalin-fixed 1-2 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Placenta or breast carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur TIMP3

Antigène: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Autre désignation: TIMP3

Sujet: HSMRK222, K222TA2, Protein MIG-5, SFD, Sorsby fundus dystrophy pseudo-inflammatory, TIMP metallopeptidase inhibitor 3, Tissue Inhibitor of Metalloproteinase 3

Poids moléculaire: ~30 kDa

ID gène: 7078

UniProt: P35625