ODC1 anticorps (CF405M)
Aperçu rapide pour ODC1 anticorps (CF405M) (ABIN6188854)
Antigène
Voir toutes ODC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Fonction
- Mouse Monoclonal anti-ODC-1 (Ornithine Decarboxylase 1) (ODC1/485), CF405M Conjugate
-
Attributs du produit
- This antibody recognizes a 53 kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
-
Immunogène
- Recombinant human ODC-1 protein
-
Isotype
- IgG1 kappa
-
-
-
-
Indications d'application
-
Immunohistology formalin-fixed 0.25-0.5 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
-
Commentaires
-
PC3 cells. Placenta, Prostate or Testicular carcinoma.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 100 μg/mL
-
Buffer
- PBS/0.1 % BSA/0.05 % azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Protect from light
-
-
- ODC1 (Ornithine Decarboxylase 1 (ODC1))
-
Autre désignation
- ODC-1 (Ornithine Decarboxylase 1)
-
Sujet
- Ornithine decarboxylase structural 1, RNODC
-
Poids moléculaire
- 53 kDa
-
ID gène
- 4953, 467701
-
UniProt
- P11926
Antigène
-