PLGF anticorps (CF®647)

N° du produit ABIN6189202

Détail du produit anti-PLGF anticorps (CF®647)

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PLGF est conjugé à/à la CF®647

Application: ELISA, Coating (Coat)

Fonction: Mouse Monoclonal anti-PLGF (PLGF/93), CF647 Conjugate

Attributs du produit: The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta, the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, PLGF appears to aid aldosterone mediated atherosclerosis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human PLGF protein

Clone: PLGF93

Isotype: IgG1 kappa

Information d'application

Indications d'application: ELISA For coating, order Ab without BSA

Commentaires:

HepG2 or HEK293T cells. Human placental and brain tumors.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur PLGF

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Autre désignation: PLGF (PGF Produits)

Synonymes: anticorps D12S1900, anticorps PGFL, anticorps PLGF, anticorps PlGF-2, anticorps SHGC-10760, anticorps AI854365, anticorps PIGF, anticorps Plgf, anticorps PlGF, anticorps placental growth factor, anticorps placenta growth factor, anticorps PGF, anticorps Pgf, anticorps PLGF

Sujet: PGFL, PIGF, placental growth factor (PGF), Vascular endothelial growth factor related protein

Poids moléculaire: 18 kDa

ID gène: 5228, 252820

UniProt: P49763

Pathways: VEGFR1 Specific Signals