ATRX anticorps (CF®568)
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- Antigène Voir toutes ATRX Anticorps
- ATRX (helicase 2, X-linked (ATRX))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ATRX est conjugé à/à la CF®568
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunostaining (ISt)
- Fonction
- Mouse Monoclonal anti-ATRX / RAD54 (39f), CF568 Conjugate
- Attributs du produit
- ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 ? to mediate chromosomal segregation. Mutations in the ATRX gene correlate with a high incidence of severe X-linked form of syndromal mental retardation associated with ? thalassemia or ATRX syndrome Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogène
- Recombinant human ATRX protein
- Clone
- 39f
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ATRX Anticorps primaire
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- Indications d'application
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Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA Buffer pH 9.0for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Commentaires
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Raji, HeLa or A431 Cells. Pancreas, Adrenal, Ovary, Kidney, Prostate or Stomach.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from light
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- Antigène
- ATRX (helicase 2, X-linked (ATRX))
- Autre désignation
- ATRX / RAD54 (ATRX Produits)
- Synonymes
- anticorps ATR2, anticorps JMS, anticorps MRXHF1, anticorps RAD54, anticorps RAD54L, anticorps SFM1, anticorps SHS, anticorps XH2, anticorps XNP, anticorps ZNF-HX, anticorps 4833408C14Rik, anticorps AI447451, anticorps DXHXS6677E, anticorps HP1-BP38, anticorps Hp1bp2, anticorps Hp1bp38, anticorps MRXS3, anticorps Rad54, anticorps Xnp, anticorps atrx, anticorps rad54, anticorps atrxl, anticorps wu:fb26e12, anticorps wu:fb52h08, anticorps wu:fb72g09, anticorps wu:fb94e07, anticorps zgc:66223, anticorps ATRX, chromatin remodeler, anticorps alpha thalassemia/mental retardation syndrome X-linked L homeolog, anticorps alpha thalassemia/mental retardation syndrome X-linked homolog (human), anticorps ATRX, anticorps Atrx, anticorps atrx.L, anticorps atrx
- Poids moléculaire
- 280 kDa
- ID gène
- 546, 533526, 653797
- UniProt
- P46100
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