TCP1 alpha/CCTA anticorps (AA 3-106) (CF®647)

N° du produit ABIN6189924

L’anticorps Souris Monoclonal anti-TCP1 alpha/CCTA a été validé pour WB, IF et FACS. Il convient pour détecter TCP1 alpha/CCTA dans des échantillons de Humain.

Aperçu rapide pour TCP1 alpha/CCTA anticorps (AA 3-106) (CF®647) (ABIN6189924)

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TCP1 alpha/CCTA est conjugé à/à la CF®647

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: TP63-1786

Détail du produit anti-TCP1 alpha/CCTA anticorps (CF®647)

Épitope: AA 3-106

Fonction: Mouse Monoclonal anti-p63 (TP63/1786), CF647 Conjugate

Attributs du produit: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human p63 protein fragment (aa3-106) (exact sequence is proprietary)

Isotype: IgG2b kappa

Information d'application

Indications d'application: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

HEK293 cells or Prostate Carcinoma or Lung or bladder squamous cell carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur TCP1 alpha/CCTA

Antigène: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Autre désignation: p63

Poids moléculaire: 63 kDa

ID gène: 8626, 137569

UniProt: Q9H3D4