Recombinant CA 19-9 anticorps (CF®647)

N° du produit ABIN6190532

Cet anticorps Lapin Monoclonal détecte spécifiquement CA 19-9 dans IHC, FACS et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant CA 19-9 anticorps (CF®647) (ABIN6190532)

Antigène: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CA 19-9 est conjugé à/à la CF®647

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: CA19-9-1390R

Détail du produit anti-CA 19-9 anticorps (CF®647)

Fonction: Recombinant Rabbit Monoclonal anti-CA19-9/Sialyl-Lewisa (CA19.9/1390R), CF647 Conjugate

Attributs du produit: CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Purified human CA19-9 protein

Isotype: IgG kappa

Information d'application

Indications d'application: Immunofluorescence 0.5-1 μg/mL Immunohistology (formalin) 5-10 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer  pH 6.0for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

Stomach or Colon Carcinoma

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur CA 19-9

Antigène: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Autre désignation: CA19-9/Sialyl-Lewisa

Sujet: CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a

Poids moléculaire: >400 kDa