Tyrosinase-Related Protein 1 anticorps (CF®488A)

N° du produit ABIN6191268

L’anticorps Souris Monoclonal anti-Tyrosinase-Related Protein 1 a été validé pour IF, FACS, WB et IHC (fro). Il convient pour détecter Tyrosinase-Related Protein 1 dans des échantillons de Humain et Souris.

Aperçu rapide pour Tyrosinase-Related Protein 1 anticorps (CF®488A) (ABIN6191268)

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Tyrosinase-Related Protein 1 est conjugé à/à la CF®488A

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: TA99 TYRP1-807

Détail du produit anti-Tyrosinase-Related Protein 1 anticorps (CF®488A)

Fonction: Mouse Monoclonal anti-TRP1 (Tyrosinase Related Protein-1) (TA99 + TYRP1/807), CF488A Conjugate

Attributs du produit: This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: SK-MEL-23 cells (TA99), Recombinant full-length human TYRP1 protein (TYRP1/807)

Isotype: IgG

Information d'application

Indications d'application: Immunohistology (frozen only) 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Commentaires:

SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells or Melanoma.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur Tyrosinase-Related Protein 1

Antigène: Tyrosinase-Related Protein 1 (TYRP1)

Autre désignation: TRP1

Poids moléculaire: 75 kDa

ID gène: 7306, 270279

UniProt: P17643