FTL anticorps (AA 38-165) (CF®594)

N° du produit ABIN6191688

L’anticorps Souris Monoclonal anti-FTL a été validé pour IHC, IF et FACS. Il convient pour détecter FTL dans des échantillons de Humain.

Aperçu rapide pour FTL anticorps (AA 38-165) (CF®594) (ABIN6191688)

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FTL est conjugé à/à la CF®594

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: FTL-1389

Détail du produit anti-FTL anticorps (CF®594)

Épitope: AA 38-165

Fonction: Mouse Monoclonal anti-Ferritin, Light chain (FTL/1389), CF594 Conjugate

Attributs du produit: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant human FTL protein fragment (aa 38-165) (exact sequence is proprietary)

Isotype: IgG1

Information d'application

Indications d'application: Immunohistology (formalin) 0.1-0.2 μg/mL

• Flow cytometry 0.1-0.2 μg/million cells Immunofluorescence 0.1-0.2 μg/mL
• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Optimal dilution for a specific application should be determined by user

Commentaires:

HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from light

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: Ferritin, Light chain

Sujet: Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

Poids moléculaire: 19-25 kDa

ID gène: 2512, 433670

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis