PD-1 anticorps (AA 21-170)

N° du produit ABIN6145334

L’anticorps anti-PD-1 Polyclonal Lapin est utilisé pour la détection de PD-1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour PD-1 anticorps (AA 21-170) (ABIN6145334)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PD-1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PD-1 anticorps

Épitope: AA 21-170

Séquence: PGWFLDSPDR PWNPPTFSPA LLVVTEGDNA TFTCSFSNTS ESFVLNWYRM SPSNQTDKLA AFPEDRSQPG QDCRFRVTQL PNGRDFHMSV VRARRNDSGT YLCGAISLAP KAQIKESLRA ELRVTERRAE VPTAHPSPSP RPAGQFQTLV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 21-170 of human PD-1/CD279 (NP_005009.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: PD-1/CD279

Sujet: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.,PDCD1,CD279,PD-1,PD1,SLEB2,hPD-1,hPD-l,hSLE1,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,PD-1/CD279

Poids moléculaire: 31 kDa

ID gène: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints