LC3A / LC3B anticorps

N° du produit ABIN6241232

Cet anticorps Souris Monoclonal détecte spécifiquement dans WB. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour LC3A / LC3B anticorps (ABIN6241232)

Antigène: LC3A / LC3B

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Clone: 3E9-E5-C9

Détail du produit

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C,-20 °C

Détail du antigène

Antigène: LC3A / LC3B

Autre désignation: LC3A/B

Sujet: LC3A:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600). LC3B:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.