RBBP5
Reactivité: Humain
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000. ICC: 1:100
Restrictions
For Research Use only
Format
Liquid
Stock
4 °C,-20 °C
Antigène
RBBP5
(Retinoblastoma Binding Protein 5 (RBBP5))
Autre désignation
RBBP5
Sujet
In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.