SAFB
Reactivité: Souris, Rat
ELISA, IHC (p), IHC (fro)
Hôte: Lapin
Polyclonal
Biotin
Indications d'application
WB: 1:1000. ICC: 1:200
Restrictions
For Research Use only
Format
Liquid
Stock
4 °C,-20 °C
Antigène
SAFB
(Scaffold Attachment Factor B (SAFB))
Autre désignation
SAFB1
Sujet
Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation.