L’anticorps anti-PEG10 Monoclonal produit chez le Souris a été validé pour WB et IP. Il convient pour la détection de PEG10 dans des échantillons provenant de Humain.
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PEG10
Reactivité: Humain, Souris
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IP: 1:500. WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Stock
4 °C,-20 °C
Antigène
PEG10
(Paternally Expressed 10 (PEG10))
Autre désignation
PEG10
Sujet
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity).