ANKRD15 anticorps

N° du produit ABIN6242162

Détail du produit anti-ANKRD15 anticorps

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ANKRD15 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This KANK1 antibody is generated from a mouse immunized with a recombinant protein of human KANK1.

Clone: 1773CT634-49-61

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur ANKRD15

Antigène: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Autre désignation: KANK1 (ANKRD15 Produits)

Synonymes: anticorps ANKRD15, anticorps CPSQ2, anticorps KANK, anticorps A930031B09Rik, anticorps AU015049, anticorps AW121052, anticorps Ankrd15, anticorps D330024H06Rik, anticorps mKIAA0172, anticorps KANK1, anticorps ankrd15, anticorps kank1.2, anticorps DMRT1, anticorps KN motif and ankyrin repeat domains 1, anticorps KN motif and ankyrin repeat domains 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1, anticorps KANK1, anticorps Kank1, anticorps kank1.L, anticorps DMRT1

Sujet: Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.

Poids moléculaire: 147289

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization