This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This EWSR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 328-362 amino acids from the Central region of human EWSR1.
EWSR1
Reactivité: Humain, Souris, Rat
WB, IHC, IF, ICC, FACS, IHC (fro)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Date de péremption
6 months
Antigène
EWSR1
(Ewing Sarcoma Breakpoint Region 1 (EWSR1))
Autre désignation
EWSR1
Sujet
Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.