XRN1 anticorps (AA 1455-1706)

N° du produit ABIN6242393

Cet anticorps Souris Monoclonal détecte spécifiquement XRN1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour XRN1 anticorps (AA 1455-1706) (ABIN6242393)

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XRN1 est non-conjugé

Application: Western Blotting (WB)

Clone: 1647CT536-85-48

Détail du produit anti-XRN1 anticorps

Épitope: AA 1455-1706

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur XRN1

Antigène: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Autre désignation: XRN1

Sujet: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Poids moléculaire: 194107

UniProt: Q8IZH2