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PFN1 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-PFN1 a été validé pour WB. Il convient pour détecter PFN1 dans des échantillons de Humain.
N° du produit ABIN6242520

Aperçu rapide pour PFN1 anticorps (C-Term) (ABIN6242520)

Antigène

Voir toutes PFN1 Anticorps
PFN1 (Profilin 1 (PFN1))

Reactivité

  • 61
  • 34
  • 33
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 69
  • 5
  • 1
Lapin

Clonalité

  • 60
  • 15
Polyclonal

Conjugué

  • 31
  • 9
  • 8
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
Cet anticorp PFN1 est non-conjugé

Application

  • 40
  • 28
  • 17
  • 15
  • 14
  • 12
  • 6
  • 5
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

RB49649
  • Épitope

    • 14
    • 8
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 87-120, C-Term

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This PFN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from the C-terminal region of human PFN1.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:8000. WB: 1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Antigène

    PFN1 (Profilin 1 (PFN1))

    Autre désignation

    PFN1

    Sujet

    Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.

    Poids moléculaire

    15054

    UniProt

    P07737

    Pathways

    Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
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