PFN1 anticorps (C-Term)
Aperçu rapide pour PFN1 anticorps (C-Term) (ABIN6242520)
Antigène
Voir toutes PFN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 87-120, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This PFN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-120 amino acids from the C-terminal region of human PFN1.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:8000. WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- PFN1 (Profilin 1 (PFN1))
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Autre désignation
- PFN1
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Sujet
- Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
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Poids moléculaire
- 15054
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UniProt
- P07737
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Pathways
- Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
Antigène
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