PDCD6 anticorps (AA 103-137)

N° du produit ABIN6242573

Détail du produit anti-PDCD6 anticorps

Antigène: PDCD6 (Programmed Cell Death 6 (PDCD6))

Épitope: AA 103-137

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDCD6 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PDCD6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human PDCD6.

Clone: RB49787

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PDCD6

Antigène: PDCD6 (Programmed Cell Death 6 (PDCD6))

Autre désignation: PDCD6 (PDCD6 Produits)

Synonymes: anticorps pdcd6, anticorps MGC52821, anticorps MGC132114, anticorps zgc:63952, anticorps PDCD6, anticorps ALG-2, anticorps PEF1B, anticorps AV299538, anticorps Alg2, anticorps MA-3, anticorps PS2, anticorps alg-2, anticorps programmed cell death 6 L homeolog, anticorps programmed cell death 6, anticorps pdcd6.L, anticorps pdcd6, anticorps PDCD6, anticorps Pdcd6

Sujet: Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity. May inhibit KDR/VEGFR2-dependent angiogenesis, the function involves inhibition of VEGF-induced phosphoprylation of the Akt signaling pathway. Seems to play a role in the regulation of the distribution and function of MCOLN1 in the endosomal pathway. Isoform 2 has a lower Ca(2+) affinity than isoform 1. Isoform 1 and, to a lesser extend, isoform 2, can stabilize SHISA5.

Poids moléculaire: 21868

UniProt: O75340

Pathways: Positive Regulation of Endopeptidase Activity