SYNE2 anticorps (AA 1843-1877)

N° du produit ABIN6242751

L’anticorps Lapin Polyclonal anti-SYNE2 a été validé pour WB et IHC (p). Il convient pour détecter SYNE2 dans des échantillons de Humain.

Aperçu rapide pour SYNE2 anticorps (AA 1843-1877) (ABIN6242751)

Antigène: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYNE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB56750

Détail du produit anti-SYNE2 anticorps

Épitope: AA 1843-1877

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SYNE2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1843-1877 amino acids from human SYNE2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur SYNE2

Antigène: SYNE2 (Spectrin Repeat Containing, Nuclear Envelope 2 (SYNE2))

Autre désignation: SYNE2

Sujet: Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein- containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Specifically, SYNE2 and SUN2 assemble in arrays of transmembrane actin-associated nuclear (TAN) lines which are bound to F-actin cables and couple the nucleus to retrograde actin flow during actin-dependent nuclear movement. Required for centrosome migration to the apical cell surface during early ciliogenesis.

Poids moléculaire: 796442

UniProt: Q8WXH0

Pathways: Maintenance of Protein Location