RUNX1 anticorps (C-Term)

N° du produit ABIN6243044

Cet anticorps Lapin Polyclonal détecte spécifiquement RUNX1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RUNX1 anticorps (C-Term) (ABIN6243044)

Antigène: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB51406

Détail du produit anti-RUNX1 anticorps

Épitope: AA 421-455, C-Term

Homologie: X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RUNX1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 421-455 amino acids from the C-terminal region of human RUNX1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur RUNX1

Antigène: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Autre désignation: RUNX1

Sujet: CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B- dependent transcriptional activation.

Poids moléculaire: 48737

UniProt: Q01196