DAXX anticorps (AA 473-502)

N° du produit ABIN6243150

L’anticorps Lapin Polyclonal anti-DAXX a été validé pour WB. Il convient pour détecter DAXX dans des échantillons de Humain.

Aperçu rapide pour DAXX anticorps (AA 473-502) (ABIN6243150)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAXX est non-conjugé

Application: Western Blotting (WB)

Clone: RB6869

Détail du produit anti-DAXX anticorps

Épitope: AA 473-502

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This DAXX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from human DAXX.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur DAXX

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Autre désignation: DAXX

Sujet: DAXX is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, this protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, this protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.

Poids moléculaire: 81373

NCBI Accession: NP_001135441, NP_001241646, NP_001341

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway