DAXX anticorps (AA 473-502)
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- Antigène Voir toutes DAXX Anticorps
- DAXX (Death-Domain Associated Protein (DAXX))
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Épitope
- AA 473-502
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DAXX est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This DAXX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-502 amino acids from human DAXX.
- Clone
- RB6869
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DAXX Anticorps primaire
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- Indications d'application
- WB: 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Date de péremption
- 6 months
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- Antigène
- DAXX (Death-Domain Associated Protein (DAXX))
- Autre désignation
- DAXX (DAXX Produits)
- Synonymes
- anticorps BING2, anticorps DAP6, anticorps EAP1, anticorps LOC100226911, anticorps daxx, anticorps si:dz179b20.7, anticorps wu:fd15c03, anticorps death domain associated protein, anticorps Fas death domain-associated protein, anticorps 28S ribosomal protein S29, mitochondrial, anticorps death-domain associated protein, anticorps death-associated protein 6 L homeolog, anticorps DAXX, anticorps Daxx, anticorps LOC100226911, anticorps daxx.L, anticorps daxx
- Sujet
- DAXX is a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, this protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, this protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.
- Poids moléculaire
- 81373
- NCBI Accession
- NP_001135441, NP_001241646, NP_001341
- UniProt
- Q9UER7
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway
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