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DNMT3A anticorps (AA 463-497)

L’anticorps anti-DNMT3A Polyclonal Lapin est utilisé pour la détection de DNMT3A dans des échantillons de Humain. Il a été validé pour WB.

Western blot analysis of lysates from Hela cell line and human skeletal muscle tissue (from left to right), using DNMT3A Antibody (Center) (ABIN6243165 and ABIN6577841). (DNMT3A anticorps (AA 463-497))

1 image

N° du produit ABIN6243165

434,77 €

Plus frais de livraison 40,00 € et TVA

Destination: France

Envoi sous 14 à 17 jours ouvrables

Aperçu rapide pour DNMT3A anticorps (AA 463-497) (ABIN6243165)

Antigène

Voir toutes DNMT3A Anticorps

DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Reactivité

Humain

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

Cet anticorp DNMT3A est non-conjugé

Application

Western Blotting (WB)

Clone

RB51574

Discover our top product DNMT3A Anticorps primaire

Épitope
16

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AA 463-497

Homologie

C, M, Rat

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène

This DNMT3A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 463-497 amino acids from the Central region of human DNMT3A.

Isotype

Ig Fraction
anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 500-700) antibody
DNMT3A Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
DNMT3A Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal RB01852 unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 26-100) antibody
DNMT3A Reactivité: Humain, Souris, Rat FACS, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 46-180) antibody
DNMT3A Reactivité: Humain IHC, ELISA, FACS Hôte: Souris Monoclonal 4G5F11 unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 457-486) antibody
DNMT3A Reactivité: Humain, Souris WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibody
DNMT3A Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 705-908), (C-Term) antibody
DNMT3A Reactivité: Humain, Souris WB, IHC, ICC, ChIP Hôte: Souris Monoclonal 64B1446 unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 1-912) antibody
DNMT3A Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) (AA 680-902) antibody
DNMT3A Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated

anti-DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A) antibody
KO Validated DNMT3A Reactivité: Humain WB, IP Hôte: Lapin Monoclonal unconjugated

Indications d'application

WB: 1:1000

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C,-20 °C

Date de péremption

6 months
Antigène

DNMT3A (DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Autre désignation

DNMT3A

Sujet

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.

Poids moléculaire

101858

UniProt

Q9Y6K1