GPR56 anticorps

N° du produit ABIN6243208

Cet anticorps anti-GPR56 est un anticorps Souris Monoclonal détectant GPR56 dans WB. Adapté pour Humain.

Aperçu rapide pour GPR56 anticorps (ABIN6243208)

Antigène: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GPR56 est non-conjugé

Application: Western Blotting (WB)

Clone: 1443CT377-65-29

Détail du produit anti-GPR56 anticorps

Immunogène: This antibody is generated from a mouse immunized with a recombinant protein.

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur GPR56

Antigène: GPR56 (G Protein-Coupled Receptor 56 (GPR56))

Autre désignation: GPR56

Sujet: Involved in cell adhesion and probably in cell-cell interactions. Regulates the migration of neural precursor cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basemant membrane integrity and in cortical lamination. Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12. Isoforms show differences in receptor signaling, specifically in serum response element (SRE) transcriptional activation upon overexpression. Overexpression inhibits melanoma tumor growth and metastasis and, during melanoma progression, regulates VEGFA production and angiogenesis through PRKCA, unprocessed GPR56 is inhibiting and GPR56 NT is activating angiogenesis.

Poids moléculaire: 77738

UniProt: Q9Y653