LMCD1 anticorps (C-Term)
Aperçu rapide pour LMCD1 anticorps (C-Term) (ABIN6243246)
Antigène
Voir toutes LMCD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 316-350, C-Term
-
Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogène
- This LMCD1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 316-350 amino acids from the C-terminal region of human LMCD1.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- WB: 1:1000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Date de péremption
- 6 months
-
-
- LMCD1 (LIM and Cysteine-Rich Domains 1 (LMCD1))
-
Autre désignation
- LMCD1
-
Sujet
- Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue- specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
-
Poids moléculaire
- 40833
-
UniProt
- Q9NZU5
Antigène
-