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SOX17 anticorps (C-Term)

L’anticorps Lapin Polyclonal anti-SOX17 a été validé pour WB. Il convient pour détecter SOX17 dans des échantillons de Humain et Souris.
N° du produit ABIN6243372

Aperçu rapide pour SOX17 anticorps (C-Term) (ABIN6243372)

Antigène

Voir toutes SOX17 Anticorps
SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Reactivité

  • 53
  • 24
  • 17
  • 9
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 38
  • 12
  • 3
Lapin

Clonalité

  • 41
  • 12
Polyclonal

Conjugué

  • 35
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SOX17 est non-conjugé

Application

  • 42
  • 14
  • 10
  • 8
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

Clone

RB51152
  • Épitope

    • 20
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 376-409, C-Term

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This (Mouse) Sox17 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of human (Mouse) Sox17.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Date de péremption

    6 months
  • Antigène

    SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

    Autre désignation

    Sox17

    Sujet

    Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'- AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity.

    Poids moléculaire

    44646

    UniProt

    Q61473
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