UHMK1 anticorps (C-Term)

N° du produit ABIN6243411

L’anticorps anti-UHMK1 Polyclonal Lapin est utilisé pour la détection de UHMK1 dans des échantillons de Humain et Souris. Il a été validé pour WB.

Aperçu rapide pour UHMK1 anticorps (C-Term) (ABIN6243411)

Antigène: UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UHMK1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB5431

Détail du produit anti-UHMK1 anticorps

Épitope: AA 265-295, C-Term

Homologie: Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-295 amino acids from the C-terminal region of human KIST (KIS).

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur UHMK1

Antigène: UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))

Autre désignation: KIST (KIS)

Sujet: KIST, a member of the Ser/Thr protein kinase family, is a pyruvate kinase that catalyzes formation of phosphoenolpyruvate from pyruvate and ATP. A role for the primarily nuclear KIST protein in mediation of cellular metabolism has been postulated based on the interaction identified with thyroid hormone. KIST is widely expressed, with highest abundance in skeletal muscle, kidney, placenta and peripheral blood leukocytes. Upon serum stimulation, KIST phosphorylates CDKN1B/p27Kip1, thereby regulating the subcellular location of CDKN1B and cell cycle progression in the G1 phase. KIST, which contains one RNA recognition motif domain, has been proposed to partipate in trafficking and processing of RNA. KIST binds to Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells.

Poids moléculaire: 46546

NCBI Accession: NP_001171692, NP_653225, NP_787062

UniProt: Q8TAS1