LARGE anticorps (AA 365-398)

N° du produit ABIN6243442

Détail du produit anti-LARGE anticorps

Antigène: LARGE (Like-Glycosyltransferase (LARGE))

Épitope: AA 365-398

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LARGE est non-conjugé

Application: Western Blotting (WB)

Homologie: C, Zf, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This LARGE antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 365-398 amino acids from the Central region of human LARGE.

Clone: RB55257

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur LARGE

Antigène: LARGE (Like-Glycosyltransferase (LARGE))

Autre désignation: LARGE (LARGE Produits)

Synonymes: anticorps gyltl1b, anticorps gyltl1b-b, anticorps mdc1d, anticorps MDC1D, anticorps MDDGA6, anticorps MDDGB6, anticorps BPFD36, anticorps Gyltl1a, anticorps Mbp-1, anticorps Mbp1, anticorps enr, anticorps fg, anticorps froggy, anticorps mKIAA0609, anticorps myd, anticorps NV15834, anticorps DKFZp459G0120, anticorps LARGE xylosyl- and glucuronyltransferase 1 L homeolog, anticorps LARGE xylosyl- and glucuronyltransferase 1, anticorps glycosyltransferase-like protein LARGE1, anticorps like-glycosyltransferase, anticorps large1.L, anticorps LARGE1, anticorps Large1, anticorps large1, anticorps LOC100118066, anticorps LARGE, anticorps Large

Sujet: Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:< a href="http://www.uniprot.org/citations/22223806" target="_blank">22223806). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide (PubMed:< a href="http://www.uniprot.org/citations/25279699" target="_blank">25279699).

Poids moléculaire: 88066

UniProt: O95461