ITGA7 anticorps (C-Term)

N° du produit ABIN6243591

Détail du produit anti-ITGA7 anticorps

Antigène: ITGA7 (Integrin, alpha 7 (ITGA7))

Épitope: AA 1149-1181, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA7 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ITGA7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1149-1181 amino acids from the C-terminal region of human ITGA7.

Clone: RB52832

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:8000. WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-ITGA7 (ABIN6243591)

Ming, Fu, Zhang, Qin, Cao, Chan, Ma, Xie, Guan: "Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma." dans: Nature communications, Vol. 7, pp. 13568, (2018) (PubMed).

Détails sur ITGA7

Antigène: ITGA7 (Integrin, alpha 7 (ITGA7))

Autre désignation: ITGA7 (ITGA7 Produits)

Synonymes: anticorps [a]7, anticorps alpha7, anticorps integrin alpha 7, anticorps integrin subunit alpha 7, anticorps Itga7, anticorps ITGA7

Sujet: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

Poids moléculaire: 128948

UniProt: Q13683

Pathways: Integrin Complex