This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This HSPA1A/HSPA1B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human HSPA1A/HSPA1B.
anticorps hsp70-4, anticorps hspa1a, anticorps Hsp70-3, anticorps Hsp70.3, anticorps Hsp72, anticorps hsp68, anticorps hsp70A1, anticorps HSP72, anticorps Hsp70-1, anticorps Hspa1, anticorps Hspa1b, anticorps hsp70-1, anticorps hsp70-1a, anticorps hsp70i, anticorps hsp72, anticorps hspa1, anticorps hspa1b, anticorps HSP70-1, anticorps HSP70-1A, anticorps HSP70I, anticorps HSPA1, anticorps HSPA1A, anticorps HSPA1B, anticorps HSP70-2, anticorps HSPA2, anticorps HSP70, anticorps hspA1A, anticorps heat shock cognate 70-kd protein, tandem duplicate 3, anticorps heat shock 70 kDa protein 1, anticorps heat shock 70 kDa protein II, anticorps heat shock protein 1A, anticorps heat shock 70kD protein 1A, anticorps heat shock protein family A (Hsp70) member 1A S homeolog, anticorps heat shock protein family A (Hsp70) member 1A, anticorps heat shock protein 70.2, anticorps heat shock 70kDa protein 1A, anticorps heat shock 70 kDa protein 1B, anticorps heat shock protein 70.1, anticorps hsp70.3, anticorps LOC100023597, anticorps LOC100554002, anticorps LOC100608888, anticorps Hspa1a, anticorps hspa1a.S, anticorps HSPA1A, anticorps HSP70.2, anticorps LOC100354037, anticorps HSP70.1
Sujet
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.