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KISS1 anticorps (AA 115-145)

KISS1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal RB53799 unconjugated
N° du produit ABIN6243763
  • Antigène Voir toutes KISS1 Anticorps
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    Épitope
    • 10
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 115-145
    Reactivité
    • 47
    • 16
    • 4
    Humain
    Hôte
    • 47
    • 4
    Lapin
    Clonalité
    • 48
    • 3
    Polyclonal
    Conjugué
    • 32
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KISS1 est non-conjugé
    Application
    • 22
    • 14
    • 14
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This KISS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the human region of human KISS1.
    Clone
    RB53799
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KISS1 Anticorps primaire
  • Indications d'application
    IF: 1:25. WB: 1:2000. WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
    Autre désignation
    KISS1 (KISS1 Produits)
    Synonymes
    anticorps HH13, anticorps KiSS-1, anticorps metastatin, anticorps Eseptin, anticorps KiSS-1 metastasis-suppressor, anticorps KISS1, anticorps kiss1, anticorps Kiss1
    Sujet
    Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine- tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
    Poids moléculaire
    14705
    UniProt
    Q15726
    Pathways
    Positive Regulation of Peptide Hormone Secretion
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