RAD21 anticorps (AA 501-535)

N° du produit ABIN6243856

Cet anticorps anti-RAD21 est un anticorps Lapin Polyclonal détectant RAD21 dans WB. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RAD21 anticorps (AA 501-535) (ABIN6243856)

Antigène: RAD21 (RAD21 Homolog (RAD21))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD21 est non-conjugé

Application: Western Blotting (WB)

Clone: RB56184

Détail du produit anti-RAD21 anticorps

Épitope: AA 501-535

Homologie: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RAD21 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 501-535 amino acids from human RAD21.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur RAD21

Antigène: RAD21 (RAD21 Homolog (RAD21))

Autre désignation: RAD21

Sujet: Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.

Poids moléculaire: 71690

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity