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RAD21 anticorps (AA 501-535)

RAD21 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal RB56184 unconjugated
N° du produit ABIN6243856
  • Antigène Voir toutes RAD21 Anticorps
    RAD21 (RAD21 Homolog (RAD21))
    Épitope
    • 16
    • 11
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-535
    Reactivité
    • 56
    • 30
    • 28
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 48
    • 6
    • 1
    Lapin
    Clonalité
    • 44
    • 12
    Polyclonal
    Conjugué
    • 34
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RAD21 est non-conjugé
    Application
    • 48
    • 17
    • 13
    • 13
    • 11
    • 11
    • 9
    • 7
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This RAD21 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 501-535 amino acids from human RAD21.
    Clone
    RB56184
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RAD21 Anticorps primaire
  • Indications d'application
    WB: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Date de péremption
    6 months
  • Antigène
    RAD21 (RAD21 Homolog (RAD21))
    Autre désignation
    RAD21 (RAD21 Produits)
    Synonymes
    anticorps rad21, anticorps wu:fb55d02, anticorps wu:fb93f04, anticorps CDLS4, anticorps HR21, anticorps HRAD21, anticorps MCD1, anticorps NXP1, anticorps SCC1, anticorps hHR21, anticorps mKIAA0078, anticorps hr21, anticorps mcd1, anticorps nxp-1, anticorps nxp1, anticorps scc1, anticorps xrad21, anticorps RAD21 cohesin complex component, anticorps RAD21 cohesin complex component a, anticorps RAD21 cohesin complex component L homeolog, anticorps RAD21 cohesin complex component S homeolog, anticorps R-spondin 2, anticorps RAD21, anticorps rad21a, anticorps rad21.L, anticorps Rad21, anticorps rad21.S, anticorps RSPO2
    Sujet
    Cleavable component of the cohesin complex, involved in chromosome cohesion during cell cycle, in DNA repair, and in apoptosis. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At metaphase-anaphase transition, this protein is cleaved by separase/ESPL1 and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Also plays a role in apoptosis, via its cleavage by caspase-3/CASP3 or caspase-7/CASP7 during early steps of apoptosis: the C-terminal 64 kDa cleavage product may act as a nuclear signal to initiate cytoplasmic events involved in the apoptotic pathway.
    Poids moléculaire
    71690
    UniProt
    O60216
    Pathways
    Positive Regulation of Endopeptidase Activity
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