R-Spondin 3 anticorps (AA 197-230)

N° du produit ABIN6243984

L’anticorps anti-R-Spondin 3 Polyclonal Lapin est utilisé pour la détection de R-Spondin 3 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour R-Spondin 3 anticorps (AA 197-230) (ABIN6243984)

Antigène: R-Spondin 3 (RSPO3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp R-Spondin 3 est non-conjugé

Application: Western Blotting (WB)

Clone: RB54572

Détail du produit anti-R-Spondin 3 anticorps

Épitope: AA 197-230

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This RSPO3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 197-230 amino acids from human RSPO3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:8000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur R-Spondin 3

Antigène: R-Spondin 3 (RSPO3)

Autre désignation: RSPO3

Sujet: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway.

Poids moléculaire: 30929

UniProt: Q9BXY4