VAMP8 anticorps (N-Term)

N° du produit ABIN6244033

Détail du produit anti-VAMP8 anticorps

Antigène: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Épitope: N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VAMP8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This VAMP8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between 2~24 amino acids from the N-terminal region of human VAMP8.

Clone: 1414CT354-12-23-93

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 1:1000-1:2000. IHC-P: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur VAMP8

Antigène: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Autre désignation: VAMP8 (VAMP8 Produits)

Synonymes: anticorps vamp8, anticorps EDB, anticorps VAMP-8, anticorps AU041171, anticorps Edb, anticorps endobrevin, anticorps wu:fa18d07, anticorps zgc:56588, anticorps vesicle associated membrane protein 8, anticorps vesicle-associated membrane protein 8 (endobrevin), anticorps vesicle-associated membrane protein 8, anticorps vamp8, anticorps VAMP8, anticorps Vamp8

Sujet: SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also required for dense-granule secretion in platelets. Plays also a role in regulated enzyme secretion in pancreatic acinar cells. Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells. Involved in the homotypic fusion of early and late endosomes.

Poids moléculaire: 11438

UniProt: Q9BV40