H3F3B anticorps (AA 31-65)
Aperçu rapide pour H3F3B anticorps (AA 31-65) (ABIN6244250)
Antigène
Voir toutes H3F3B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 31-65
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This H3f3b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-65 amino acids from human H3f3b.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- H3F3B (H3 Histone, Family 3B (H3.3B) (H3F3B))
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Autre désignation
- H3f3b
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Sujet
- Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Poids moléculaire
- 15328
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UniProt
- P84244
Antigène
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