Mare/Nprl3/C16orf35 anticorps (AA 86-117)
Aperçu rapide pour Mare/Nprl3/C16orf35 anticorps (AA 86-117) (ABIN6244303)
Antigène
Voir toutes Mare/Nprl3/C16orf35 (C16orf35) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 86-117
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This NPRL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from human NPRL3.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Date de péremption
- 6 months
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- Mare/Nprl3/C16orf35 (C16orf35) (MARE (C16orf35))
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Autre désignation
- NPRL3
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Sujet
- As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC- containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.
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Poids moléculaire
- 63605
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UniProt
- Q12980
Antigène
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