Podoplanin anticorps (AA 24-126)

N° du produit ABIN6252118

Détail du produit anti-Podoplanin anticorps

Antigène: Podoplanin (PDPN)

Épitope: AA 24-126

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Podoplanin est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Protein G affinity chromatography

Immunogène: A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.

Clone: PDPN-1433

Isotype: IgG1 kappa

Information d'application

Indications d'application: WB: 0.5-1 μg/mL

IF: 0.5-1 μg/mL

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Optimal dilution of the Podoplanin antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur Podoplanin

Antigène: Podoplanin (PDPN)

Autre désignation: Podoplanin (PDPN Produits)

Synonymes: anticorps PDPN, anticorps AGGRUS, anticorps GP36, anticorps GP40, anticorps Gp38, anticorps HT1A-1, anticorps OTS8, anticorps PA2.26, anticorps T1A, anticorps T1A-2, anticorps OTS-8, anticorps RANDAM-2, anticorps T1-alpha, anticorps T1a, anticorps T1alpha, anticorps E11, anticorps RTI40, anticorps podoplanin, anticorps PDPN, anticorps Pdpn

Sujet: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

ID gène: 10630

UniProt: Q86YL7

Pathways: Dicarboxylic Acid Transport