Podoplanin anticorps (AA 24-126)
Aperçu rapide pour Podoplanin anticorps (AA 24-126) (ABIN6252118)
Antigène
Voir toutes Podoplanin (PDPN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 24-126
-
Purification
- Protein G affinity chromatography
-
Immunogène
- A human recombinant partial protein corresponding to amino acids 24-126 was used as the immunogen for the Podoplanin antibody.
-
Isotype
- IgG1 kappa
-
-
-
-
Indications d'application
-
WB: 0.5-1 μg/mL
IF: 0.5-1 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
Optimal dilution of the Podoplanin antibody should be determined by the researcher. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.2 mg/mL
-
Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
-
-
- Podoplanin (PDPN)
-
Autre désignation
- Podoplanin
-
Sujet
- Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
-
ID gène
- 10630
-
UniProt
- Q86YL7
-
Pathways
- Dicarboxylic Acid Transport
Antigène
-