CD1b anticorps

N° du produit ABIN6252383

Cet anticorps anti-CD1b est un anticorps Souris Monoclonal détectant CD1b dans FACS, IF et Func. Adapté pour Humain.

Aperçu rapide pour CD1b anticorps (ABIN6252383)

Antigène: CD1b (CD1B)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD1b est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: RIV12

Détail du produit anti-CD1b anticorps

Purification: Protein G affinity chromatography

Immunogène: Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Functional testing: order BSA/azide free format

IF: 0.5-1 μg/mL

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD1b antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur CD1b

Antigène: CD1b (CD1B)

Autre désignation: CD1b

Sujet: This antibody recognizes CD1b, a 44  kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.

ID gène: 910

UniProt: P29016