FSHR anticorps
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- Antigène Voir toutes FSHR Anticorps
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FSHR est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Purification
- Protein G affinity chromatography
- Immunogène
- A human recombinant protein was used as the immunogen for this FSHR antibody.
- Clone
- FSHR-1400
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product FSHR Anticorps primaire
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- Indications d'application
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Flow Cytometry: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 min at RT
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FSHR antibody to be titered up or down for optimal performance. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Antigène
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- Autre désignation
- FSH Receptor (FSHR Produits)
- Synonymes
- anticorps FSHRO, anticorps LGR1, anticorps ODG1, anticorps FSH-R, anticorps eFSHR, anticorps FSHRE, anticorps fshr, anticorps FSHR, anticorps fshr-A, anticorps GTHR-I, anticorps zfGTHR-I, anticorps LOC100304505, anticorps follicle stimulating hormone receptor, anticorps follicle stimulating hormone receptor L homeolog, anticorps follicle-stimulating hormone receptor, anticorps FSHR, anticorps fshr, anticorps Fshr, anticorps fshr.L, anticorps Bm1_17785, anticorps LOC100304505
- Sujet
- Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its alpha and beta subunits. While the alpha subunit of FSH is involved in the binding of FSH to the receptor, the beta subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells.
- ID gène
- 2492
- UniProt
- P23945
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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