LGALS1/Galectin 1 anticorps (AA 12-108)
Aperçu rapide pour LGALS1/Galectin 1 anticorps (AA 12-108) (ABIN6252495)
Antigène
Voir toutes LGALS1/Galectin 1 (LGALS1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 12-108
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Purification
- Protein G affinity chromatography
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Immunogène
- A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.
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Isotype
- IgG1 lambda
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Indications d'application
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ELISA: 2-4 μg/mL, order the BSA-free formulation for coating
IF: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
Titering of the Galectin 1 antibody may be required for optimal performance. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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Autre désignation
- Galectin 1
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Sujet
- Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.
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ID gène
- 3956
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UniProt
- P09382
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Pathways
- Carbohydrate Homeostasis
Antigène
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