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Filaggrin anticorps (AA 998-1104)

FLG Reactivité: Humain IHC, WB, IF, FACS Hôte: Souris Monoclonal FLG-1561 unconjugated
N° du produit ABIN6252502
  • Antigène Voir toutes Filaggrin (FLG) Anticorps
    Filaggrin (FLG)
    Épitope
    • 15
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 998-1104
    Reactivité
    • 64
    • 18
    • 12
    Humain
    Hôte
    • 48
    • 23
    Souris
    Clonalité
    • 43
    • 28
    Monoclonal
    Conjugué
    • 42
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Filaggrin est non-conjugé
    Application
    • 37
    • 31
    • 24
    • 24
    • 13
    • 13
    • 9
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    Protein G affinity chromatography
    Immunogène
    Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.
    Clone
    FLG-1561
    Isotype
    IgG
    Top Product
    Discover our top product FLG Anticorps primaire
  • Indications d'application
    Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

    IF: 1-2 μg/mL

    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

    Optimal dilution of the Filaggrin antibody should be determined by the researcher.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Antigène
    Filaggrin (FLG)
    Autre désignation
    Filaggrin (FLG Produits)
    Synonymes
    anticorps AW107830, anticorps ft, anticorps FLG, anticorps ATOD2, anticorps Pflg, anticorps Flg, anticorps filaggrin, anticorps Flg, anticorps FLG, anticorps LOC100351762, anticorps LOC100728006
    Sujet
    Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
    ID gène
    2312
    UniProt
    P20930
    Pathways
    Sensory Perception of Sound, Stem Cell Maintenance
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