Nkx2-2 anticorps

N° du produit ABIN6252568

L’anticorps Lapin Polyclonal anti-Nkx2-2 a été validé pour IF, IHC et FACS. Il convient pour détecter Nkx2-2 dans des échantillons de Humain.

Aperçu rapide pour Nkx2-2 anticorps (ABIN6252568)

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nkx2-2 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-Nkx2-2 anticorps

Purification: Protein A affinity chromatography

Immunogène: A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/10e6 cells in 0.1ml

IF: 1-2 μg/mL

IHC (FFPE): 1-2 μg/mL for 30 minutes at RT

Titering of the NKX2.2 antibody may be required for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur Nkx2-2

Antigène: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Autre désignation: NKX2.2

Sujet: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.

ID gène: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis