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Liver Arginase anticorps (ARG1, C-Term)

ARG1 Reactivité: Humain WB, IHC (p), IF Hôte: Souris Monoclonal T1ARG-1 unconjugated
N° du produit ABIN6252586
  • Antigène Voir toutes Liver Arginase (ARG1) Anticorps
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Épitope
    • 24
    • 19
    • 16
    • 12
    • 12
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ARG1, C-Term
    Reactivité
    • 110
    • 64
    • 42
    • 9
    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 110
    • 29
    • 5
    • 3
    • 2
    Souris
    Clonalité
    • 108
    • 41
    Monoclonal
    Conjugué
    • 84
    • 13
    • 11
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Liver Arginase est non-conjugé
    Application
    • 101
    • 59
    • 36
    • 30
    • 21
    • 20
    • 16
    • 14
    • 13
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    Protein G affinity chromatography
    Immunogène
    A C-terminal recombinant protein fragment from ARG1 was used as the immunogen for the Arginase 1 antibody.
    Clone
    T1ARG-1
    Isotype
    IgG3 kappa
    Top Product
    Discover our top product ARG1 Anticorps primaire
  • Indications d'application
    Immunofluorescence: 1-2 μg/mL

    Western blot: 0.5-1 μg/mL

    Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT (1)

    Prediluted format : incubate for 30 min at RT (2)

    Optimal dilution of the Arginase 1 antibody should be determined by the researcher.

    1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Antigène
    Liver Arginase (ARG1) (Arginase, Liver (ARG1))
    Autre désignation
    Arginase 1 (ARG1 Produits)
    Synonymes
    anticorps SI:zC146F4.4 (novel protein with NUDIX domain), anticorps si:ch211-146f4.3, anticorps argi1, anticorps AI, anticorps AI256583, anticorps Arg-1, anticorps PGIF, anticorps arginase 1, anticorps arginase, anticorps Arginase-1, anticorps arginase, liver, anticorps L-arginase, anticorps arg1, anticorps PGTG_16455, anticorps argi1, anticorps ARG1, anticorps Arg1
    Sujet
    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [RefSeq]
    ID gène
    383
    UniProt
    P05089
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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