Villin 1 anticorps (AA 179-311)

N° du produit ABIN6252737

Cet anticorps anti-Villin 1 Monoclonal Souris (Clone VIL1-1314) (ABIN6252737) détecte spécifiquement Villin 1 dans WB, FACS, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Villin 1 anticorps (AA 179-311) (ABIN6252737)

Antigène: Villin 1 (VIL1)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Villin 1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: VIL1-1314

Détail du produit anti-Villin 1 anticorps

Épitope: AA 179-311

Purification: Protein G affinity chromatography

Immunogène: Amino acids 179-311 from the human protein were used as the immunogen for this Villin antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow Cytometry: 0.5-1 μg/10^6 cells in 0.1ml

IF: 1-2 μg/mL

Western blot: 1-2 μg/mL

IHC (FFPE): 0.25-0.5 μg/mL for 30 min at RT

Titration of the Villin antibody may be required for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Détails sur Villin 1

Antigène: Villin 1 (VIL1)

Autre désignation: Villin

Sujet: Recognizes a protein of ~93  kDa which is identified as Villin (VIL1). It is a major constituent in the microvilli, which compose the brush border of epithelial cells forming absorptive surfaces of the intestinal and renal proximal tubular epithelia. Anti-Villin labels the brush border area in the gastrointestinal mucosal epithelium and urogenital tract. Among neoplasms, Villin is predominantly expressed in tumors of colorectal origin. Antibody to Villin is useful in identifying malignant cells from primary and metastatic colorectal carcinomas. This antibody also labels Merkel cells of the skin.

ID gène: 7429

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization